COMPOSITION Moxarif 500 Capsule: Each capsule contains Amoxicillin Trihydrate BP equivalent to Amoxicillin 500 mg. Moxarif Powder for Suspension: After reconstitution, each 5 ml suspension contains Amoxicillin 250 mg as Amoxicillin Trihydrate BP. PHARMACOLOGY Amoxicillin is a semi synthetic antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. Amoxicillin kills bacteria by interfering with the synthesis of the bacterial cell wall. Amoxicillin is stable at gastric pH. It is completely absorbed in the upper gastrointestinal tract. Absorption is independent of meals. INDICATION Moxarif is indicated in the treatment of infections due to susceptible strains of the designated microorganisms in the condition listed below: Upper and Lower Respiratory Tract Infections (Including ENT): Acute and chronic bronchitis, lobar and bronchopneumonia, tonsillitis, pharyngitis, laryngitis, sinusitis, otitis media. Infections of the genitourinary tract: Cystitis, urethritis, pyelonephritis, septic abortion, puerperal sepsis, intra-abdominal sepsis. Infection of the Digestive tract: Typhoid, Para-typhoid. Skin and soft tissue Infections Sexually transmited disease: Gonorrhea, Syphilis, acute uncomplicated ano-genital and urethral infections. H. pylori eradication to reduce the risk of duodenal ulcer recurrence in combination with clarithromycin plus omeprazole as triple therapy. Moxarif may also be used as a prophylactic for patients at risk of developing endocarditis when undergoing dental surgery