BANGAY CREAM

Menthol + Methyl Salicylate Cream

Composition:

Each 100 gram of cream contains 10 g of Menthol USP and 30 g of Methyl Salicylate BP.

Pharmacology:

Each of the ingredients within the combination shows distinct function in reduction of pain.

Menthol exerts cooling and soothing effect by stimulating the cold receptor and thus

causes reduction of pain. Methyl Salicylate is converted to salicylic acid and causes the

inhibition of cyclooxygenase enzyme. As a result prostaglandin synthesis is being inhibited

and that ultimately results in reduction of pain.

Indications:

This combined preparation provides temporary relief of minor aches and pains of muscles

and joints associated with backache, lumbago, strains, bruises, sprains and arthritis or

rheumatic pain, pain of tendons and ligaments. Several double-blind clinical studies of this

product containing Methyl Salicylate and Menthol have shown the effectiveness of this

combination in counteracting minor pain of skeletal muscle stress and arthritis.

Dosage and Application:

Adults and Children 2 years of age and older: Apply generously to the painful area and

gently massage until the cream disappears. Apply to affected area not more than 3 to 4

times daily. If condition worsens, or if symptoms persist for more than 7 days or clear-up and

occur again within a few days, discontinue use of this product and consult a doctor.

Children below 2 years of age: Sufficient data is not available for use of this product in

children below 2 years of age

Side Effects:

Redness or irritation may occur, especially in persons with sensitive skin. Adverse reactions

possibly involved are mild to moderate local irritation, erythema, rash, desquamation,

pruritis and relative local reaction at the application site.

Contraindications:

Contraindicated in patients with bleeding disorders, allergy to Salicylate or sensitivity to any

of the components.Application to broken skin or raw surfaces is not recommended.

Precautions:

For external use only.Use only as directed.Does not use with a heating pad. Keep away from

children to avoid accidental poisoning. Do not use tight bandage. Do not swallow. If

swallowed, induce vomiting and call a physician. Keep away from eyes, mucous membranes,

broken or irritated skin. If skin redness or irritation develops, pain lasts for more than 10 days,

or with arthritis-like conditions in children under 12, do not use and call a physician. Long

term and excess administration may cause skin irritation and redness. So the cream should

be administered according to recommended dose.Therapy might be hazardous for patients

with impaired kidney or liver function or for smaller children.

Drug Interactions:

Methyl Salicylate is systemically absorbed through the skin in measurable amounts and may

increase Warfarin action by affecting vitamin K metabolism or by displacing Warfarin from

protein-binding sites.

Storage :

Maintain the temperature between 20°and 25° C (68° and 77°F). Store in a cool and dry

place.

Packing:

BANGAY Cream: Lamitube containing 15/25 g of cream